Cut the chuck roast into 3 or 4 large pieces
Season all over with minced onions, garlic powder, sea salt and pepper, and set aside
Hit SAUTE on the Instant Pot, and when it reads Hot, add the olive oil and sliced onions. Cook until slightly soft or longer for more caramelization
Add the red wine, beef broth and Worcestershire sauce, and deglaze pot with wooden spoon or spatula. Allow liquid to cook for about 2 to 3 minutes to reduce slightly. (optional)
Press CANCEL, then place seasoned beef into pressure cooker, and press to make sure most of it is in the liquid
Add lid, make sure vent is at Sealing position, and hit PRESSURE COOK for 60 minutes
Pot will take a few minutes to reach pressure and begin counting down as it cooks. When pot beeps, allow a 15 minute release, then turn vent to quick release remaining pressure
When pin drops, remove lid, shred meat, and return to pot to keep warm